Sustained release pharmaceutical compounds to prevent abuse of controlled substances
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United States of America Patent
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Nov 24, 2009
Grant Date -
Apr 14, 2005
app pub date -
Aug 23, 2004
filing date -
Feb 22, 2002
priority date (Note) -
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Abstract
The present invention provides methods for altering controlled substances in a manner that decreases their potential for abuse. The novel compounds may be combined in tablets with suitable excipients or formulated in solution for oral delivery. When delivered by the oral route the controlled substance is released in a time-dependent manner (sustained release) by acid hydrolysis and/or enzymatic cleavage. When administered by injection the controlled substance is released in a time-dependent manner (sustained release) by way of serum enzymes.
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