Systems and methods for combined RF-induced hyperthermia and radioimmunotherapy

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United States of America Patent

PATENT NO 7627381
APP PUB NO 20050273143A1
SERIAL NO

11050478

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A combined radiotherapy and hyperthermia therapy is provided, including inducing hyperthermia in at least a portion of a target area—e.g., a tumor or a portion of a tumor or targeted cancerous cells—is provided. Biomolecules labeled with at least one radionuclide suitable for radiotherapy are provided and introduced into a patient; targeted RF absorption enhancers are provided and introduced into a patient; and a hyperthermia generating RF signal is directed via toward the target cells, thereby warming the radionuclide-labeled biomolecules and targeted RF absorption enhancers bound to target cells. The targeted RF absorption enhancers may, in a manner of speaking, add one or more RF absorption frequencies to cells in the target area, which will permit a hyperthermia generating RF signal at that frequency or frequencies to heat the targeted cells. Biomolecules labeled with at least one radionuclide suitable for radiotherapy may be used for both radiotherapy and as RF absorption enhancers for the hyperthermia generating RF signal.

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Patent Owner(s)

Patent OwnerAddress
NEOTHERMA ONCOLOGY INCP O BOX 487 WICHITA KS 67201

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kanzius, John Erie , US 6 648
Keating, Michael J Houston , US 43 1575
McDonald, Robert J Sanibel , US 10 80
Steinbrink, William Harry Erie , US 2 59

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