US Patent No: 7,632,521
Number of patents in Portfolio can not be more than 2000
Controlled release potassium chloride tablets
Stats
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Dec 15, 2009
Issued date -
Jul 15, 2003
filing date -
10/619,924
serial no -
In Force
status
Importance
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Abstract
A unit dosage form, such as a tablet for delivering potassium into the body in a controlled release fashion, comprises of a multiplicity of microencapsulated potassium chloride crystals, which are further coated with a plasticized polymer to improve compressibility of the microcapsules. The compressible microcapsules are blended with a compression aid, such as microcrystalline cellulose and a glidant, such as colloidal silicon dioxide, to form controlled release potassium chloride tablets. The tablets may optionally include other excipients such as surfactants and disintegrants. The tablets thus produced exhibit not only high crushing strength and low friability but also release potassium in humans in a desired controlled release fashion similar to commercially available potassium chloride tablets.
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First Claim
Related Publications
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International Classification(s)
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- [Patents Count]
Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 5,252,337 Controlled release calcium channel blocker microcapsules | 21 | 1991 | |
| 5,422,122 Controlled release potassium chloride tablet | 11 | 1992 | |
| 5,622,723 Procedure for encapsulating chlorpheniramine | 3 | 1995 | |
| 5,639,475 Effervescent microcapsules | 41 | 1995 | |
| 5,651,984 Controlled release potassium tablet | 7 | 1995 | |
| 5,653,993 Procedure for encapsulating ibuprofen | 7 | 1995 | |
| 5,814,332 Procedure for encapsulating ibuprofen | 5 | 1997 | |
| 6,139,865 Taste-masked microcapsule compositions and methods of manufacture | 34 | 1997 | |
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| 4,508,702 Sustained release aspirin | 11 | 1984 | |
| 4,555,399 Aspirin tablet | 38 | 1984 | |
| 4,634,587 Sustained release quinidine dosage form | 18 | 1984 | |
| 4,587,118 Dry sustained release theophylline oral formulation | 41 | 1984 | |
| 4,863,743 Controlled release potassium chloride | 16 | 1986 | |
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| 4,519,801 Osmotic device with wall comprising cellulose ether and permeability enhancer | 60 | 1982 | |
| 4,553,973 Process for preparing osmotic device | 30 | 1985 | |
| 4,915,953 Dosage form for delivering acetaminophen or phenylpropanolamine | 44 | 1989 | |
| 5,156,850 Dosage form for time-varying patterns of drug delivery | 28 | 1990 | |
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| 5,397,574 Controlled release potassium dosage form | 10 | 1993 | |
| 5,567,441 Diltiazem controlled release formulation | 64 | 1995 | |
| 6,210,716 Controlled release bupropion formulation | 18 | 1999 | |
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| 5,219,574 Magnesium carbonate and oil tableting aid and flavoring additive | 31 | 1991 | |
| 5,223,264 Pediatric effervescent dosage form | 81 | 1991 | |
| 5,178,878 Effervescent dosage form with microparticles | 150 | 1992 | |
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| 4,389,331 Process for preparing pharmaceutically active compound-containing microcapsules | 10 | 1980 | |
| 4,462,982 Microcapsules and method of preparing same | 42 | 1982 | |
| 4,542,042 Process for preparing free-flowing ethylcellulose microcapsules | 13 | 1983 | |
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| 4,994,260 Pharmaceutical mixture | 25 | 1985 | |
| 5,085,868 Liquid dosage form for all oral administration of a pharmaceutically active substance | 15 | 1990 | |
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| 4,666,703 Storage-stable, quick-disintegrating pressed shapes containing pharmaceutical active substances | 38 | 1985 | |
| 4,954,349 Oral magnesium and potassium compositions and use | 10 | 1989 | |
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| 4,898,737 Controlled absorption pharmaceutical composition | 11 | 1988 | |
| 5,505,962 Controlled release pharmaceutical formulation | 12 | 1994 | |
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| 5,709,886 Effervescent microcapsules | 39 | 1997 | |
| 6,451,345 Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration | 9 | 2000 | |
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| 4,460,563 Process for preparing microcapsules in a liquid vehicle | 85 | 1981 | |
| 5,409,711 Pharmaceutical formulations | 43 | 1991 | |
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| 4,800,087 Taste-masked pharmaceutical compositions | 90 | 1986 | |
| 5,084,278 Taste-masked pharmaceutical compositions | 89 | 1989 | |
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| 4,572,833 Method for preparing a pharmaceutical controlled release composition | 74 | 1983 | |
| 4,716,041 Diffusion coated multiple-units dosage form | 70 | 1985 | |
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| 5,472,712 Controlled-release formulations coated with aqueous dispersions of ethylcellulose | 109 | 1993 | |
| 6,316,031 Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer | 15 | 1999 | |
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| 4,193,985 Multiple-units drug dose | 60 | 1978 | |
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| 4,713,248 Diffusion coated multiple-units dosage form | 65 | 1985 | |
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| 4,316,884 Sustained release pharmaceutical formulation | 28 | 1980 | |
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| 4,389,330 Microencapsulation process | 262 | 1980 | |
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| 4,259,315 Controlled release potassium dosage form | 38 | 1980 | |
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| 4,574,080 Combination formulation | 25 | 1983 | |
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| 5,840,329 Pulsatile drug delivery system | 132 | 1997 | |
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| 2006/0222,699 FLAVORED VEGETARIAN CELLULOSE CAPSULE AND METHODS FOR PRODUCING SAID CAPSULE. | 1 | 2005 | |
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| 5,082,669 Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked | 26 | 1990 | |
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| 5,133,974 Extended release pharmaceutical formulations | 201 | 1990 | |
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| 5,180,587 Tablet formulations of pesticides | 12 | 1990 | |
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| 5,137,730 Tablet composition and method for problem pharmaceutical materials using citric acid | 12 | 1991 | |
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| 5,192,552 Process for preparing microcapsules providing the rapid release of a drug as active ingredient | 5 | 1989 | |
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| 4,748,023 Process for the preparation of sustained release pharmaceutical compositions having a high active ingredient content | 34 | 1984 | |
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| 4,952,402 Controlled release powder and process for its preparation | 157 | 1988 | |
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| 4,820,627 Method of preparing particles suitable for tabletting into diagnostic reagents | 29 | 1986 | |
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| 5,464,632 Rapidly disintegratable multiparticular tablet | 113 | 1994 | |
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| 5,008,117 Formulation for preparing extemporaneous homogeneous microcapsule suspension | 21 | 1988 | |
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| 4,895,836 Nor-cholanic acid derivatives, a process for their preparation, their use and pharmaceutical compositions containing them | 5 | 1987 | |
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| 5,002,774 Sustained release pharmaceutical tablet | 15 | 1989 | |
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| 4,629,620 Membrane-coated sustained-release tablets and method | 27 | 1985 | |
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| 4,182,778 Encapsulation of vitamin and mineral nutrients | 20 | 1978 | |
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| 5,879,706 Valaciclovir tablets containing colloidal silicon dioxide | 10 | 1997 | |
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| 5,578,316 Palatable pharmaceutical compositions | 12 | 1995 | |
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| 5,215,756 Preparation of pharmaceutical and other matrix systems by solid-state dissolution | 24 | 1990 | |
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| 4,524,060 Slow release pharmaceutical composition | 52 | 1983 | |
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| 5,229,134 Pharmaceutical compositions | 14 | 1990 | |
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| 5,807,579 Pseudoephedrine combination pharmaceutical compositions | 37 | 1996 | |
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| 5,075,114 Taste masking and sustained release coatings for pharmaceuticals | 69 | 1990 | |
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| 5,073,377 Method of preparing oral dosage forms with a granulating composition | 20 | 1990 | |
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| 5,238,688 Method for preparing a powdered particulate composition | 5 | 1990 | |
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| 5,032,406 Dual-action tablet | 42 | 1989 | |
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| 4,321,253 Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration | 26 | 1980 | |
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| 4,432,966 Compressed tablets for disintegration in the colon comprising an active ingredient containing nucleus coated with a first layer containing microcrystalline cellulose which is coated with an enteric organic polymer coating | 78 | 1982 | |
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| 5,073,374 Fast dissolving buccal tablet | 57 | 1988 | |
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| 4,302,440 Easily-swallowed, powder-free and gastric-disintegrable aspirin tablet thinly-coated with hydroxypropyl methylcellulose and aqueous spray-coating preparation thereof | 37 | 1980 | |
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| 5,126,145 Controlled release tablet containing water soluble medicament | 97 | 1990 | |
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| 4,971,791 Taste masking compositions | 12 | 1990 | |
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| 4,832,955 Controlled release potassium chloride composition | 7 | 1988 | |
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| 4,777,044 Therapeutic preparation having ammonium nitrate as its active substance | 1 | 1987 | |
| 2008/0207,673 Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins | 2 | 2006 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Jun 15, 2013 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Jun 15, 2017 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jun 15, 2021 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 3.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |