Cell nucleus-entering compositions
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United States of America Patent
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Dec 29, 2009
Grant Date -
May 11, 2006
app pub date -
Oct 3, 2005
filing date -
Oct 1, 2004
priority date (Note) -
Withdrawn
status (Latency Note)
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Abstract
A pharmaceutically acceptable composition and method for entering a cell nucleus utilizes a cell nucleus-entering polypeptide including at least one of amino acid sequence LKKTET (SEQ ID NO:1), amino acid sequence LKKTNT (SEQ ID NO:2) or amino acid sequence KSKLKK (SEQ ID NO:3), or a conservative variant thereof, linked to a physiologically active agent having at least one of therapeutic or diagnostic application in the cell nucleus.
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