US Patent No: 7,642,074

Number of patents in Portfolio can not be more than 2000

PUFA polyketide synthase systems and uses thereof

Stats

ALSO PUBLISHED AS: 20070256146
ATTORNEY / AGENT: (SPONSORED)
 

Importance

Loading Importance Indicators... loading....

Abstract

The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.

Loading the Abstract Image... loading....

First Claim

Related Publications

Loading Related Publications... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
DSM IP ASSETS B.V.6411 TE HEERLEN1137

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barclay, William R Boulder, CO 140 2389
Flatt, James H Longmont, CO 70 1396
Metz, James G Longmont, CO 123 2072
Weaver, Craig A Boulder, CO 82 1283

Cited Art

Patent Info (Count) # Cites Year
 
DSM IP ASSETS B.V. (38)
5,130,242 Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids 177 1990
5,908,622 Food product containing thraustochytrium and/or schizochytrium microflora and an additional agricultural based ingredient 68 1997
6,566,583 Schizochytrium PKS genes 63 1999
7,001,772 Product and process for transformation of Thraustochytriales microorganisms 55 2002
7,247,461 Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof 31 2002
7,214,853 Schizochytrium PKS genes 45 2002
7,211,418 PUFA polyketide synthase systems and uses thereof 51 2004
7,217,856 PUFA polyketide synthase systems and uses thereof 51 2004
7,256,022 Pufa polyketide synthase systems and uses thereof 45 2005
7,256,023 PUFA polyketide synthase systems and uses thereof 46 2005
7,259,295 PUFA polyketide synthase systems and uses thereof 45 2005
7,271,315 PUFA polyketide synthase systems and uses thereof 51 2006
2007/0244,192 PLANT SEED OILS CONTAINING POLYUNSATURATED FATTY ACIDS 51 2007
2007/0270,494 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS 48 2007
2008/0026,434 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0026,435 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0026,438 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0026,439 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0026,440 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0032,351 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0038,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0022,422 CHIMERIC PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 49 2007
2008/0148,433 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0038,792 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0044,867 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0038,793 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,794 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 41 2007
2008/0038,795 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,796 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 41 2007
2008/0038,797 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0040,822 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,868 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 41 2007
2008/0044,869 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 41 2007
2008/0044,871 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,872 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,873 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0050,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 40 2007
 
SAGAMI CHEMICAL RESEARCH CENTER (3)
5,246,841 Microbial process for production of eicosapentaenoic acid 60 1991
5,683,898 Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid 64 1995
5,798,259 Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid 52 1996
 
ABBOTT LABORATORIES (2)
6,677,145 Elongase genes and uses thereof 49 2001
7,208,590 Genes involved in polyketide synthase pathways and uses thereof 20 2003
 
E. I. DU PONT DE NEMOURS AND COMPANY (2)
2004/0172,682 Production of very long chain polyunsaturated fatty acids in oilseed plants 52 2004
7,125,672 Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts 60 2004
 
MARTEK BIOSCIENCES CORPORATION (2)
2008/0038,378 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 35 2007
2008/0038,379 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
 
MONSANTO COMPANY (2)
5,639,790 Plant medium-chain thioesterases 93 1993
6,140,486 Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants 81 1998
 
BIORIGINAL FOOD & SCIENCE CORP. (1)
7,087,432 Fad4, Fad5, Fad5-2 and Fad6, novel fatty acid desaturase family members and uses thereof 44 2001
 
BIOTICA TECHNOLOGY LIMITED (1)
6,033,883 Production of polyketides in bacteria and yeast 76 1997
 
IACR-ROTHAMSTED (1)
2005/0089,865 Delta 6 desaturases from primulaceae, expressing plants and pufa-containing oils 52 2004
 
KOSAN BIOSCIENCES, INC. (1)
2004/0005,672 Heterologous production of polyketides 51 2003
 
MIAMI UNIVERSITY, AN OHIO CORPORATION (1)
2004/0139,498 Fatty acid elongase 3-ketoacyl CoA synthase polypeptides 44 2004
 
ROCHE DIAGNOSTICS GMBH (1)
6,503,706 Method for identifying human and animal cells having an unlimited proliferation of tumor-formation potential 47 1996
 
SEMBIOSYS GENETICS INC. (1)
2007/0245,431 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS 51 2007
 
SUPERMEDIA LLC (1)
2008/0044,870 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
5,672,491 Recombinant production of novel polyketides 159 1994
 
THE UNIVERSITY OF YORK (1)
2005/0164,192 Transgenic plants expressing enzymes involved in fatty acid biosynthesis 92 2005
 
WASHINGTON STATE UNIVERSITY (1)
2004/0010,817 Plant acyl-CoA synthetases 44 2003
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (1)
5,310,242 Portable infant seat 56 1992

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
DSM IP ASSETS B.V. (1)
8,309,796 Chimeric PUFA polyketide synthase systems and uses thereof 0 2011

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Jul 5, 2013
7.5 Year Payment $3600.00 $1800.00 $900.00 Jul 5, 2017
11.5 Year Payment $7400.00 $3700.00 $1850.00 Jul 5, 2021
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00