Sterol/stanol phosphorylnitroderivatives and use thereof
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United States of America Patent
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Jan 12, 2010
Grant Date -
Oct 4, 2007
app pub date -
Apr 3, 2006
filing date -
Apr 3, 2006
priority date (Note) -
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Abstract
Sterol and stanol phosphorylnitro derivatives and their use in treating or preventing cardiovascular disease, its underlying conditions and other disorders are disclosed. The disclosed compounds include a phosphate linker, at least one moiety that releases nitric oxide (NO), and a sterol or stanol moiety. Some compounds additionally include an ascorbyl moiety to make the compound more readily soluble in aqueous and non-aqueous media.
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