Compounds and methods for labeling oligonucleotides
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United States of America Patent
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Jan 12, 2010
Grant Date -
Dec 3, 2009
app pub date -
Aug 4, 2009
filing date -
May 20, 2005
priority date (Note) -
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Abstract
The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below.The invention further provides compositions comprising labeled oligonucleotides and solid supports. The invention also provides kits comprising at least one composition of the present invention.
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