Synthesis of taxol enhancers

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United States of America Patent

PATENT NO 7652168
APP PUB NO 20090005594A1
SERIAL NO

12231217

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Abstract

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Disclosed is a method of preparing a thiohydrazide product compound from a hydrazide starting compound. The hydrazide starting compound is represented by Structural Formula (I):The thiohydrazide product compound is represented by Structural Formula (II):is —H or a substituted or unsubstituted alkyl group. The method comprising the step of reacting the starting compound with a thionylating reagent.

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SYNTA PHARMACEUTICALS CORP99 HAYDEN AVENUE LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Shoujun Billerica, US 116 1525
Kova, Keizo Brookline, US 2 26
Ono, Mitsunori Lexington, US 120 1577
Sun, Lijun Harvard, US 223 2689
Xia, Zhi-Qiang Dedham, US 29 569

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