US Patent No: 7,655,228

Number of patents in Portfolio can not be more than 2000

Method of modulating the activity of functional immune molecules to GM2

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ALSO PUBLISHED AS: 20070166303
ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like, an agent of promoting the activity of an immunologically functional molecule, and an immunologically functional molecule having the promoted activity.

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First Claim

Related Publications

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Patent Owner(s)

Patent OwnerAddressTotal Patents
KYOWA HAKKO KIRIN CO., LTD.TOKYO270

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Anazawa, Hideharu Tokyo, JP 42 385
Hanai, Nobuo Machida, JP 115 925
Hosaka, Emi Machida, JP 63 566
Imabeppu, Susumu Ube, JP 21 294
Kanda, Yutaka Machida, JP 103 742
Nakamura, Kazuyasu Machida, JP 107 757
Shinkawa, Toyohide Machida, JP 51 578
Uchida, Kazuhisa Machida, JP 60 641
Yamane, Naoko Machida, JP 51 572
Yamasaki, Motoo Machida, JP 109 793

Cited Art

Patent Info (Count) # Cites Year
 
KYOWA HAKKO KIRIN CO., LTD. (24)
5,830,470 Humanized antibodies to ganglioside GM.sub.2 40 1993
6,018,032 Antibody against human interleukin-5-receptor .alpha. chain 29 1997
6,437,098 Human chimeric antibody specific for the ganglioside GD3 22 1999
6,986,890 Anti-human VEGF receptor Flt-1 monoclonal antibody 22 1999
6,946,292 Cells producing antibody compositions with increased antibody dependent cytotoxic activity 56 2001
2003/0175,273 Human CDR-grafted antibody and antibody fragment thereof 20 2002
2004/0110,282 Cells in which activity of the protein involved in transportation of GDP-fucose is reduced or lost 30 2003
2004/0132,140 Production process for antibody composition 35 2003
2005/0187,380 Method for treating Th2-mediated disease 20 2005
7,214,775 Method of modulating the activity of functional immune molecules 50 2005
2005/0272,916 Method of modulating the activity of functional immune molecules 27 2005
2006/0024,800 Method of modulating the activity of functional immune molecules 24 2005
2005/0216,958 Cells of which genome is modified 21 2005
2005/0262,593 Antibody composition-producing cell 23 2005
2006/0223,147 Process for producing glycoprotein composition 22 2005
2006/0063,254 Antibody composition-producing cell 25 2005
2006/0064,781 Antibody composition-producing cell 28 2005
2007/0010,009 Antibody Composition-Producing Cell 19 2006
2007/0166,300 Method of Modulating the Activity of Functional Immune Molecules 20 2007
2007/0166,301 Method of Modulating the Activity of Functional Immune Molecules 20 2007
2007/0166,302 Method of Modulating the Activity of Functional Immune Molecules 20 2007
2007/0166,303 Method of Modulating the Activity of Functional Immune Molecules 20 2007
2007/0166,304 Method of Modulating the Activity of Functional Immune Molecules 20 2007
2008/0261,301 Antibody Composition-Producing Cell 19 2008
 
GENENTECH, INC. (5)
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6,737,056 Polypeptide variants with altered effector function 141 2000
2003/0157,108 Glycoprotein compositions 75 2002
7,297,775 Polypeptide variants 29 2002
 
KYOWA HAKKO KOGYO CO., LTD. (5)
2004/0093,621 Antibody composition which specifically binds to CD20 49 2002
2004/0110,704 Cells of which genome is modified 37 2003
2005/0160,485 Mouse in which genome is modified 20 2004
2005/0226,867 IL-5R-specific antibody composition 21 2004
2005/0287,138 CCR4-specific antibody composition 22 2004
 
ROCHE GLYCART AG (4)
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2004/0072,290 Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity 44 2003
2005/0074,843 Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity 32 2003
2007/0111,281 Antigen binding molecules having modified Fc regions and altered binding to Fc receptors 26 2006
 
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6,498,015 Methods of identifying agents that modulate the binding between MDC and an MDC receptor 27 1997
 
MILLENNIUM PHARMACEUTICALS, INC. (2)
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TANIGUCHI, NAOYUKI (2)
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6,291,219 .alpha.1-6 fucosyltransferase 20 1999
 
TOUDAI TLO, LTD. (2)
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2005/0048,647 Sirna expression system and process for producing functional gene knockdown cell or the like using the same 31 2004
 
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (2)
5,977,316 Monoclonal antibody 1A7 and related polypeptides 28 1996
5,935,821 Polynucleotides related to monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma 35 1996
 
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BIOGEN IDEC MA INC. (1)
7,033,589 γ-1 anti-human CD23 monoclonal antibodies and use thereof as therapeutics 22 1999
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
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CENTRO DE INMUNOLOGIA MOLECULAR (1)
5,891,996 Humanized and chimeric monoclonal antibodies that recognize epidermal growth factor receptor (EGF-R); diagnostic and therapeutic use 62 1995
 
CHUGAI SEIYAKU KABUSHIKI KAISHA (1)
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DESMOS, INC. (1)
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FUJITSU LIMITED (1)
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GENETICS INSTITUTE, LLC (1)
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GLAXO GROUP LIMITED (1)
6,150,132 Chemokine receptor able to bind to MCP-1, MIP-1.alpha. and/or RANTES. Its uses 38 1997
 
HAZLETON BIOTECHNOLOGIES, INC. (1)
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IDEC PHARMACEUTICALS CORPORATION (1)
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LEUKOSITE, INC. (1)
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OSAKA UNIVERSITY (1)
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PANASONIC CORPORATION OF NORTH AMERICA (1)
2007/0166,305 Method of Modulating the Activity of Functional Immune Molecules 20 2007
 
SMITHKLINE BEECHAM P.L.C. (1)
6,129,913 Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders 24 1997
 
SRD PHARMACEUTICALS, INC. (1)
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STRYKER CORPORATION (1)
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THE GENERAL HOSPITAL CORPORATION (1)
5,858,983 Inhibition of cell adhesion protein-carbohydrate interactions 34 1995
 
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (1)
6,238,894 .alpha.1,2 fucosyltransferase 24 1999
 
THE GREEN CROSS CORPORATION (1)
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THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (1)
6,350,868 Antisense human fucosyltransferase sequences and methods of use thereof 22 2000
 
UNIVERSITY OF UTAH (1)
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WISTAR INSTITUTE, THE, A CORP. OF PA (1)
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Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
KYOWA HAKKO KIRIN CO., LTD. (8)
8,067,232 Antibody composition-producing cell with inactivated A-1,6-fusocyltransferase 0 2008
7,846,725 Antibody composition-producing cell in which enzyme expression is inhibited by RNAi 7 2008
8,158,760 Glycoengineered, recombinant antibody 0 2009
8,039,595 Glycoengineered, recombinant antibody to CCR-4 with reduced fucosylation 0 2009
8,367,407 Cells with altered fucosylation and producing antibodies therefrom 0 2009
8,110,195 Antibody composition exhibiting cellular cytotoxicity due to glycosylation and containing ganglioside GM2 binding antibody 0 2010
8,101,185 Anti-il-5 antibody composition exhibiting cellular cytotoxicity due to glycosylation 0 2010
8,329,443 Antibody composition-producing cell 0 2011

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