Methods and devices for diagnosis of appendicitis
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United States of America Patent
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Feb 9, 2010
Grant Date -
Oct 25, 2007
app pub date -
Feb 2, 2007
filing date -
Jul 23, 2004
priority date (Note) -
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Abstract
A method is provided for determining the severity of appendicitis in a patient that includes testing a blood, serum or plasma sample from the patient for the quantity of MRP8/14 in the sample and comparing it with the quantity of MRP8/14 present in standard samples correlated with an appendicitis severity scoring system. A histologically-based appendicitis severity scoring system is also provided. Immunoassays and kits for performing the appendicitis assays of this invention are also provided, as are standard samples and data correlating MRP8/14 quantities present in patient samples to histologically-based appendicitis severity grades. The methods and immunoassay devices and kits of this invention are useful for managing the treatment of patients presenting with appendicitis symptoms.
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