Osteoimplant and method for making same
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United States of America Patent
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Feb 16, 2010
Grant Date -
Jul 19, 2007
app pub date -
Feb 19, 2007
filing date -
Jun 8, 1999
priority date (Note) -
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Abstract
A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a depth of at least about 100 microns; and, configuring the monolithic section of cortical bone to provide an osteoimplant possessing an outer surface possessing at least one demineralized zone and a non-demineralized zone. An implant produced according to the above method demonstrates improved osteoinduction without producing any clinically significant reduction of strength in critical regions of the osteoimplant.
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