Method for analyzing dynamic detectable events at the single molecule level
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United States of America Patent
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Feb 23, 2010
Grant Date -
Oct 25, 2007
app pub date -
Feb 6, 2007
filing date -
Feb 6, 2006
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Abstract
A method to be implemented on or in a computer is disclosed, where the method includes data collection, calibration, candidate selection, and analysis of data streams associated with each candidate to classify single molecule fluorescence resonance energy transfer events. Once classified, the classification can be related to the nature of the events, such as the identification of dNTP incorporation during primer extension to obtain a base read out of an unknown template.
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