Methods and compositions for whole genome amplification and genotyping
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United States of America Patent
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Mar 2, 2010
Grant Date -
Mar 17, 2005
app pub date -
Jun 17, 2004
filing date -
Jun 20, 2003
priority date (Note) -
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Abstract
This invention provides methods of amplifying genomic DNA to obtain an amplified representative population of genome fragments. Methods are further provided for obtaining amplified genomic DNA representations of a desired complexity. The invention further provides methods for simultaneously detecting large numbers of typable loci for an amplified representative population of genome fragments. Accordingly the methods can be used to genotype individuals on a genome-wide scale.
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