US Patent No: 7,674,596
Number of patents in Portfolio can not be more than 2000
Transfected cell line and a method using the same for the high throughput screening for inhibitors of the T-type calcium channel alpha-1H
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Mar 9, 2010
Issued date -
Sep 12, 2005
filing date -
11/162,487
serial no -
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Abstract
The present invention relates to a cell line in which a potassium channel is introduced. More specifically, it is a cell line capable of activating the T-type α1H calcium channel by depolarization wherein a vector encoding a potassium channel is introduced. Since the cell line of the present invention is available for a high throughput screening of candidate T-type α1H calcium channel inhibitors, it may accelerate the development of therapeutic agents for diseases related to T-type α1H calcium channels.
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First Claim
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 6,576,434 Methods for identification of agents which modulate chloride channel activity | 1 | 2001 | |
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| 6,984,521 HEK293 cell line for activity studies and HTS system of α1G T-type Ca2+ channel | 1 | 2004 | |
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| 6,899,800 Polymeric electrode for electrophysiological testing | 3 | 2002 | |
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| 2004/0121,381 Methods and compositions for screening ICRAC modulators | 1 | 2003 | |
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