Particles for inhalation having sustained release properties

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United States of America Patent

PATENT NO 7678364
APP PUB NO 20020034477A1
SERIAL NO

09822716

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to particles suitable for use in the method. In particular, the invention relates to a method for the pulmonary delivery of a therapeutic, prophylactic or diagnostic agent comprising administering to the respiratory tract of a patient in need of treatment, prophylaxis or diagnosis an effective amount of particles comprising a multivalent metal cation which is complexed with a therapeutic, prophylactic or diagnostic agent or any combination thereof having a charge capable of complexing with the cation upon association with the agent, a pharmaceutically acceptable carrier and optionally, a multivalent metal cation-containing component wherein the total amount of multivalent metal cation present in the particles is more than 1% weight/weight of the total weight of the agent (% w/w). Release of the agent from the administered particles occurs in a sustained fashion.

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Patent Owner(s)

Patent OwnerAddress
MERZ PHARMACEUTICALS LLC6601 SIX FORKS ROAD 4TH FLOOR RALEIGH NC 27615

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Edwards, David A Boston, US 150 5736
Hrkach, Jeffrey S Cambridge, US 37 2011

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