Sphingomyelin therapy of autoimmune disease

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7683044
APP PUB NO 20080096845A1
SERIAL NO

11857303

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Autoimmune disease therapy in a patient treated with apoptosis-inducing agents is enhanced by co-administration of sphingomyelin. The combination most likely enhances an autoimmune disease cell's ability to undergo ceramide-induced apoptosis by increasing the levels of sphingomyelin in all cellular compartments, thereby providing sufficient substrate for activated sphingomyelinase. In alternative embodiments, sphingomyelin may be administered alone, in combination with corticosteroids, and/or in combination with a apoptosis-inducing agent.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGYONE BRUCE STREET NEWARK NJ 07103-2763 UNITED STATES OF AMERICA

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goldenberg, David M Mendham, US 527 13665
Modrak, David E Nutley, US 1 0

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation