Method for the preparation of trans-or cis-diammoniumdichlorodihydroxoplatinum(IV) and the use thereof in the production of pharmaceutical active substances
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United States of America Patent
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Mar 30, 2010
Grant Date -
Dec 13, 2007
app pub date -
Oct 13, 2004
filing date -
Oct 13, 2003
priority date (Note) -
Expired
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Abstract
The invention relates to a method for the preparation of trans- or cis-diammoniumdichlorodihydroxoplatinum(IV) and derivatives thereof. What is suggested is reacting trans- or cis-diammoniumdichloroplatinum(II) with a solution comprising >30% peroxide at temperatures below 30° C. and dissolving the product thus obtained in a mineral acid and subsequently precipitating with an alkaline solution.
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