Polynucleotides encoding acetylcholine-gated chloride channel subunits of Caenorhabditis elegans
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United States of America Patent
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Apr 20, 2010
Grant Date -
Oct 23, 2008
app pub date -
Jun 8, 2005
filing date -
Jun 9, 2004
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Expired
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Abstract
The invention relates to novel polynucleotides which encode novel polypeptides that are acetylcholine-gated chloride channel subunits and immunogenic or acetylcholine-binding fragments thereof. The novel polypeptides may be used for identifying compounds that modulate the acetylcholine-gated chloride channels, e.g. for use as pesticides and antiparasitic agents. Methods for identifying compounds that modulate the acetylcholine-gated chloride channels are provided.
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