Arctic β amyloid protofibril
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United States of America Patent
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Apr 20, 2010
Grant Date -
Oct 25, 2007
app pub date -
Jan 18, 2007
filing date -
Jul 7, 2000
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Abstract
The present invention relates to prevention and treatment of Alzheimer's disease (AD). More specifically, the invention relates to use of a non-wild type protofibril or compound(s) with protofibril forming activity for active immunisation in the purpose of treating or preventing AD. The invention further relates to a peptide, Aβ-Arc, with high protofibril forming activity as well as several applications thereof, such as antibodies against said peptide for passive immunisation against AD.
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