Methods for treating and preventing infectious disease

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United States of America Patent

PATENT NO 7713529
APP PUB NO 20030191079A1
SERIAL NO

10306522

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Abstract

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Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful as a synthetic adjuvant.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF IOWA RESEARCH FOUNDATION200 S CAPITOL STREET 2660 UNIVERSITY CAPITOL CENTRE IOWA CITY IOWA 52242 52242

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Klinman, Dennis Potomac, US 68 4430
Krieg, Arthur M Iowa City, US 154 11149
Steinberg, Alfred D Potomac, US 51 3951

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