Cytotoxic compounds and conjugates with cleavable substrates
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United States of America Patent
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May 11, 2010
Grant Date -
Nov 2, 2006
app pub date -
Apr 6, 2006
filing date -
Apr 8, 2005
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Abstract
The present disclosure provides drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-cleavable substrate conjugates, and to methods of treatment using them.
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