Polynucleotides encoding the fkbB gene of the FK-520 polyketide synthase gene cluster
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United States of America Patent
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May 11, 2010
Grant Date -
Jul 23, 2009
app pub date -
Jul 6, 2004
filing date -
Oct 2, 1998
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Abstract
Host cells comprising recombinant vectors encoding the FK-520 polyketide synthase and FK-520 modification enzymes can be used to produce the FK-520 polyketide. Recombinant DNA constructs comprising one or more FK-520 polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variety of different polyketides with application as pharmaceutical and veterinary products.
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