Methods and pharmaceutical compositions for reliable achievement of acceptable serum testosterone levels
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United States of America Patent
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May 18, 2010
Grant Date -
Feb 10, 2005
app pub date -
Mar 12, 2004
filing date -
Mar 14, 2003
priority date (Note) -
In Force
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Abstract
The present invention relates to pharmaceutical compositions, formulated for injectable administration, which comprises a testosterone ester, in particularly testosterone undecanoate, in a vehicle comprising castor oil and a co-solvent. Upon injecting the compositions according to a particular administration scheme, reliable levels of testosterone in serum in the normal physiological range is achieved for a long period. This allows for the use of the compositions in hormone replacement therapy and male contraception without concomitant monitoring of testosterone levels in serum by a physician.
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