Conditions for reactions mediated by yeast
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United States of America Patent
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May 25, 2010
Grant Date -
Apr 21, 2005
app pub date -
Mar 31, 2004
filing date -
Oct 16, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Organic compounds, such as precursors for aryl ethylamines such as ephedrine, aryl propylamines such as fluoxetine and propionic acid derivatives such as ibuprofen, naproxen and fenoprofen, are subjected to a yeast mediated reduction conducted in the absence of a solvent. The yeast is moistened with water and contacted with the organic compound. The yeast may then be contacted with an organic solvent to dissolve the product of the reaction into the solvent, and a solid/liquid separation used to separate the product from the yeast.
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