Dynamic monitoring of cell adhesion and spreading using the RT-CES system
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United States of America Patent
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Jun 8, 2010
Grant Date -
Jun 8, 2006
app pub date -
Sep 27, 2005
filing date -
Dec 20, 2002
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Abstract
The present invention includes devices and methods for dynamically monitoring cell adhesion and cell spreading. Cells are added to a microelectronic cell sensor array operably connected to an impedance analyzer. The device also includes a coating including biological molecule or organic compound capable of interacting with the cell. Cell adhesion and cell mobility is determined by detecting changes in impedance and comparing impedance or cell index values between samples.
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