Approach to antimicrobial host defense with molecular shields with EPA and DHA analogs

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United States of America Patent

PATENT NO 7741368
APP PUB NO 20060128804A1
SERIAL NO

11353436

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Abstract

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Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. Various BPI inducing agents include icosapentanoic acid (EPA) analogs and docosahexaenoic acid (DHA) analogs.

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Patent Owner(s)

Patent OwnerAddress
THE BRIGHAM AND WOMEN'S HOSPITAL INC75 FRANCIS STREET BOSTON MA 02115

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Colgan, Sean P Newton, US 16 150
Serhan, Charles N Needham, US 122 1258

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