Reduced bioirritant composition
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United States of America Patent
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Jun 29, 2010
Grant Date -
Mar 16, 2006
app pub date -
Oct 19, 2005
filing date -
Jun 28, 1999
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method for reducing irritancy of ascorbic acid administered to a biological surface for anti-angiogenic, anti-oxidant, anti-inflammatory and other effects. It has been discovered that pH neutralized ascorbic acid retains the efficacy of non-pH neutralized ascorbic acid in reducing neovascularization, providing an anti-oxidant effect, etc. but is less irritating and thus enhances patient comfort and compliance. It may be administered into or on the eye, on skin, into a body cavity, etc. either alone or with other agents.
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