N- or C- terminally modified small peptides
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United States of America Patent
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Jul 6, 2010
Grant Date -
May 31, 2007
app pub date -
Jul 7, 2006
filing date -
Jul 7, 2005
priority date (Note) -
Expired
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Abstract
N- or C-terminally modified small peptides having antiarrhythmic properties are disclosed, and in particular small peptides that possess improved pharmacokinetic properties such as having a reduced tendency to inhibit the activity of isozyme 3A4 of cytochrome P 450 oxidase. The invention further relates to uses of said compounds in the preparation of a medicament, and to pharmaceutical compositions comprising said compounds.
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