Cyanine dye labelling reagents
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United States of America Patent
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Jul 6, 2010
Grant Date -
Aug 30, 2007
app pub date -
Oct 29, 2004
filing date -
Oct 31, 2003
priority date (Note) -
Expired
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Abstract
—W, where W is sulphonic acid or phosphonic acid and k is an integer from 1 to 10. The dyes may be used in fluorescence labeling applications, where the presence of one and preferably multiple water solubilising groups attached to the 3-position of the indolinium ring reduces dye-dye interactions, and hence dye-dye quenching, particularly where multiple dye molecules are attached to components such as nucleic acids, oligonucleotides, proteins and antibodies.
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