Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins
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United States of America Patent
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Aug 10, 2010
Grant Date -
Apr 28, 2005
app pub date -
Sep 10, 2004
filing date -
Sep 12, 2003
priority date (Note) -
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Abstract
Osteogenic proteins are delivered via an injectable solid rod or hardenable paste. The formulation comprises a calcium phosphate material, an osteogenic protein, and optional additives and active ingredients such as a bone resorption inhibitor. Methods of making injectable pharmaceutical compositions and methods of using the osteogenic compositions to treat bone defects are also disclosed.
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