Gene cluster of pederin biosynthesis genes
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United States of America Patent
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Aug 10, 2010
Grant Date -
Jun 2, 2005
app pub date -
Nov 21, 2002
filing date -
Nov 22, 2001
priority date (Note) -
Expired
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Abstract
The present invention relates to the cloning, sequencing and analysing of a gene cluster encoding a modular polyketide synthase enzyme involved in the biosynthesis of the antitumor compound pederin. This novel cluster represents the first example of genes from an unculturable symbiont encoding the biosynthesis of a drug candidate.
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