Mammalian IAP gene family, primers, probes and detection methods
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United States of America Patent
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Aug 17, 2010
Grant Date -
Feb 22, 2007
app pub date -
Aug 3, 2006
filing date -
Aug 4, 1995
priority date (Note) -
Expired
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Abstract
Disclosed is substantially pure DNA encoding mammalian IAP polypeptides; and methods of using such DNA to express the IAP polypeptides in cells and animals to inhibit apoptosis. Also disclosed are conserved regions characteristic of the IAP family and primer and probes for the identification and isolation of additional IAP genes. In addition, methods for treating diseases and disorders involving apoptosis are provided.
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