Pyrimido[5,4-d]pyrimidines derivatives as irreversible inhibitors of tyrosine kinases
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United States of America Patent
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Aug 31, 2010
Grant Date -
Dec 11, 2003
app pub date -
May 20, 2003
filing date -
Apr 12, 1996
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Abstract
The present invention relates to pyrimido [5,4-d] pyrimidine compounds of Formula II or a pharmaceutically acceptable salt thereof,wherein Q isand p are as defined herein. The compounds of this invention are irreversible inhibitors of tyrosine kinases and are useful in the treatment of cancer, atherosclerosis, restenosis, endometriosis and psoriasis.
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