Method and apparatus of mechanical stage positioning in virtual microscopy image capture
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United States of America Patent
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Sep 7, 2010
Grant Date -
Feb 16, 2006
app pub date -
Aug 11, 2005
filing date -
Aug 16, 2004
priority date (Note) -
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status (Latency Note)
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Abstract
A method and apparatus for creating a magnified composite image of a microscope specimen comprises making error corrections for imprecise movements of the specimen relative to an objective lens when capturing data for first and second images. A correction offset is computed based on a comparison of data for overlapped portions of the first and second images and then the specimen is moved through a distance modified by the correction offset for capture of a subsequent tiled image. Image center portions are retained as the data structure tile. The area about the center portion is used to align images and to compensate for stage inaccuracies and to provide a feedback signal for a drive system. Differences in X, Y coordinates for macro and micro view images may be used as navigation offsets to view a selected point for the micro image marked on the macro image.
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