Medicament incorporation matrix
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United States of America Patent
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Sep 14, 2010
Grant Date -
Jul 27, 2006
app pub date -
Mar 23, 2006
filing date -
Aug 15, 2000
priority date (Note) -
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status (Latency Note)
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Abstract
A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating composition provides a gel matrix adapted to contain the medicament in a form that permits the medicament to be released from the matrix in a prolonged, controlled, predictable and effective manner in vivo. A composition includes a polyether monomer, such as an alkoxy poly(alkylene glycol), a carboxylic acid-containing monomer, such as (meth)acrylic acid, a photoderivatized monomer, and a hydrophilic monomer such as acrylamide.
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