Detection and measurement of thyroid hormone autoantibodies
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United States of America Patent
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Sep 21, 2010
Grant Date -
May 13, 2010
app pub date -
Nov 12, 2008
filing date -
Nov 12, 2008
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Abstract
A non-radioisotopic method detects T3AA and T4AA thyroid autoantibodies in a sample from a non-human species such as the canine species. Antibodies and autoantibodies are bound, and a precipitated or bound antigen-antibody or antigen-autoantibody complex is formed. The supernatant or surrounding fluid of the bound or precipitated antigen-antibody or antigen-autoantibody complex is then removed. The thyroid activity of the bound complex, precipitate, supernatant or surrounding fluid is measured. The thyroid analyte is at least one of T3, Free T3, T4 or Free T4.
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