Decontamination of surfaces contaminated with prion-infected material with gaseous oxidizing agents
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United States of America Patent
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Sep 28, 2010
Grant Date -
May 8, 2003
app pub date -
Apr 3, 2002
filing date -
Oct 5, 2001
priority date (Note) -
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Abstract
A surface which carries a material which is infected with prions is cleaned with an alkaline cleaning solution to remove as much proteinaceous material as possible from the surface. The solution contains an alkaline cleaning agent which attacks prions remaining on the surface and which attacks prions removed from the surface during the cleaning step. After the cleaning step, the surface is exposed to a strong gaseous oxidant, preferably hydrogen peroxide vapor. The hydrogen peroxide or other strong oxidant attacks the prions, particularly the unclumped prion strands, deactivating the prions.
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