Process for preparing purified drug conjugates
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United States of America Patent
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Oct 12, 2010
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app pub date -
Aug 14, 2006
filing date -
Aug 24, 2005
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Abstract
The invention provides a process for preparing a cell-binding agent chemically coupled to a drug. The process comprises covalently attaching a linker to a cell-binding agent, a purification step, conjugating a drug to the cell-binding agent and a subsequent purification step.
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