Analysing polynucleotide sequences
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United States of America Patent
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Oct 12, 2010
Grant Date -
Aug 21, 2003
app pub date -
Apr 4, 2002
filing date -
May 3, 1988
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention provides an apparatus and method for analyzing a polynucleotide sequence, either an unknown sequence or a known sequence. A support carries an array of the whole or a chosen part of a complete set of oligonucleotides, which are capable of taking part in hybridization reactions. The polynucleotide sequence, or fragments thereof, are labeled and applied to the array under hybridizing conditions. Applications include analysis of known point mutations, genomic fingerprinting, linkage analysis, characterization of mRNAs, mRNA populations, and sequence determination.
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