Engineering β-ketoacyl ACP synthase for novel substrate specificity
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United States of America Patent
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Oct 12, 2010
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Mar 19, 2009
app pub date -
Oct 23, 2008
filing date -
Jun 9, 1999
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Abstract
Methods of altering substrate specificity of beta-ketoacyl-ACP synthase, and engineered beta-ketoacyl-ACP synthases so produced are provided. DNA sequences and constructs for expression of engineered beta-ketoacyl-ACP synthases, as well as the novel beta-ketoacyl-ACP synthases produced therefrom are also provided. Such DNA sequences may be used for expression of the engineered beta-ketoacyl-ACP synthases in host cells, particularly seed cells of oilseed crop plants, for the modification of fatty acid composition.
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