Methods for the treatment of multiple myeloma

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United States of America Patent

PATENT NO 7825088
SERIAL NO

11409927

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Abstract

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Methods for treating multiple myeloma with inhibitors of CXCR4 are described. The decreased expression of CXCR4 on multiple myeloma cells according to the invention results in decreased homing of the cells to the bone marrow and a reduction in the development of the disease. Also disclosed are pharmaceutical compositions incorporating such inhibitors for use in the therapeutic treatment of multiple myeloma. The treatment methods described herein can be used independently, or in conjunction with, other therapies for the treatment of multiple myeloma.

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Patent Owner(s)

Patent OwnerAddress
CBR INSTITUTE FOR BIOMEDICAL RESEARCH INC THE800 HUNTINGTON AVENUE BOSTON MA 02115

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gauguet, Jean-Marc Boston, US 2 9
Mazo, Irina Chestnut Hill, US 2 9
von, Andrian Ulrich H Brookline, US 19 463

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