US Patent No: 7,825,133

Number of patents in Portfolio can not be more than 2000

Derivatives of pyridone and the use of them

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ALSO PUBLISHED AS: 20070049624
ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

The present invention provides N-substituted-2(1H) pyridones or the pharmaceutical acceptable salts thereof, and the pharmaceutical preparations containing the compounds. The compounds of the present invention can be used to treat various fibrotic diseases effectively, e.g., hepatic fibrosis.

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First Claim

Related Publications

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Patent Owner(s)

Patent OwnerAddressTotal Patents
SHANGHAI GENOMICS, INC.SHANGHAI, CN6

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Yi, Xianghui Shanghai, CN 6 8

Cited Art

Patent Info (Count) # Cites Year
 
INTERMUNE, INC. (6)
5,310,562 Composition and method for reparation and prevention of fibrotic lesions 27 1992
5,962,478 Inhibition of tumor necrosis factor .alpha. 10 1998
6,090,822 Treatment of cytokine growth factor caused disorders 13 1998
6,300,349 Inhibition of tumor necrosis factor alpha 12 1999
6,956,044 Compositions and methods for treatment of epilepsy 6 2000
2006/0110,358 Combination therapy for treatment of fibrotic disorders 13 2003
 
EISAI R&D MANAGEMENT CO., LTD. (2)
2006/0100,249 Pharmaceutical compositions comprising dihydropyridinone compounds and an immunoregulatory or an antiinflammatory agent and their uses 7 2002
2006/0276,510 Dihydropyridine compounds and compositions for headaches 5 2006
 
IMPERIAL CHEMICAL INDUSTRIES PLC (2)
4,866,078 Phenyl pyridones and insectidal use thereof 3 1987
5,039,807 Phenyl pyrid(-one or-thione) compounds which are intermediates 3 1989
 
KUMIAI CHEMICAL INDUSTRY CO., LTD. (2)
6,048,823 Pyridone derivatives and herbicides 5 1998
6,265,349 Pyridone derivatives and herbicides 4 1999
 
MEPHA AG (2)
6,492,395 Topical formulation of alkyl-, phenyl-pyridone 9 2001
2006/0039,931 Stable cream preparations of phenyl-pyridone compounds for topical application 32 2003
 
PHARMACIA LLC (2)
7,067,540 Substituted pyridinones 6 2003
2006/0211,694 Diaryl substituted pyridinones 4 2005
 
BASF AKTIENGESELLSCHAFT (1)
2003/0216,257 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides 4 2003
 
CORNELL RESEARCH FOUNDATION, INC. (1)
5,789,426 Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation 8 1995
 
DALHOUSIE UNIVERSITY (1)
6,294,350 Methods for treating fibroproliferative diseases 18 1999
 
KDL, INC (1)
2006/0167,064 Pharmaceutical liquid composition containing pyridone derivative 4 2003
 
MERCK & CO., INC. (1)
5,939,439 Inhibitors of farnesyl-protein transferase 16 1997
 
OLYMPUS CORPORATION (1)
2006/0279,709 Light source device and projection optical device 6 2006
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (1)
5,716,632 Compositions and methods for reparation and prevention of fibrotic lesions 21 1996

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
Z-MEDICA, LLC (6)
8,257,731 Devices and methods for the delivery of molecular sieve materials for the formation of blood clots 1 2009
8,114,433 Clay-based hemostatic agents and devices for the delivery thereof 5 2009
8,202,532 Clay-based hemostatic agents and devices for the delivery thereof 2 2009
8,257,732 Clay-based hemostatic agents and devices for the delivery thereof 1 2011
8,343,537 Clay-based hemostatic agents and devices for the delivery thereof 0 2012
8,383,148 Clay-based hemostatic agents and devices for the delivery thereof 0 2012
 
Z-MEDICA (1)
8,252,344 Partially hydrated hemostatic agent 1 2004

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 May 2, 2014
7.5 Year Payment $3600.00 $1800.00 $900.00 May 2, 2018
11.5 Year Payment $7400.00 $3700.00 $1850.00 May 2, 2022
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00