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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address	Total Patents
METABASIS THERAPEUTICS, INC.	SAN DIEGO, CA	47

International Classification(s)

• C07F:ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CO....
• A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....

• [Classification Symbol]

• [Patents Count]

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Boyer, Serge H	San Diego, US	15	200
Erion, Mark D	Del Mar, US	65	1443
Jiang, Hongjian	San Diego, US	12	42

Cited Art Landscape

Patent Info	(Count)	# Cites	Year
Other [Check patent profile for assignment information] (3)
2003/0040,535 Tetrazole compounds as thyroid receptor ligands		7	2002
2003/0114,521 Oxamic acids and derivatives as thyroid receptor ligands		2	2002
2005/0054,727 Phenyl naphthol ligands for thyroid hormone receptor		2	2004
NOVARTIS CORPORATION (3)
5401772 Heteroacetic acid derivatives		32	1993
5569674 Heteroacetic acid derivatives		27	1994
5654468 Heteroacetic acid derivatives		19	1996
SYNTEX (U.S.A.) INC. (1)
5284971 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents		34	1992
SHIRE LLC (1)
2004/0152,783 Controlled absorption of admixed thyroid hormone formulations		2	2003
NOVARTIS AG (2)
6117873 Substituted aminoalkane phosphonic acids		12	1999
6689896 Thyromimetic organic compounds		2	2001
NICHOLAS BACHYNSKY, M.D., P.A., TX (1)
4673691 Human weight loss inducing method		12	1984
ABBVIE DEUTSCHLAND GMBH & CO KG (1)
5753254 Therapeutic agents containing thyroid hormones		37	1996
NORWEST BANK, ARIZONA, NATIONAL ASSOCIATION (1)
5951989 Method for the treatment of dry skin		54	1997
NEW RIVER PHARMACEUTICALS INC. (1)
2004/0116,391 Stabilized thyroxine compounds		5	2003
Dr. Karl Thomae GmbH (1)
5232946 Phenylethanolamines, their use as pharmaceuticals and as performance enhancers in animals		17	1990
SMITHKLINE BEECHAM P.L.C. (1)
5741803 Substituted thiazolidinedionle derivatives		20	1995
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (1)
6852706 Methods and compositions for healing heart wounds		8	2001
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (1)
6361992 Thyroid stimulating hormone superagonists		27	1998
PFIZER INC. (5)
6194454 Cyano containing oxamic acids and derivatives as thyroid receptor ligands		48	2000
6326398 Oxamic acids and derivatives as thyroid receptor ligands		10	2000
6620830 Thyroid receptor ligands		8	2001
6545018 Oxamic acids and derivatives as thyroid receptor ligands		6	2001
6723744 Indole carboxylic acids as thyroid receptor ligands		6	2002
TAKEDA PHARMACEUTICAL COMPANY LIMITED (1)
6982348 Aminoethanol derivatives		16	2002
CIBA-GEIGY CORPORATION (1)
4554290 Oxamic acid derivatives		11	1984
Hoechst Aktiengesellschaft (1)
5627173 Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders		2	1996
PFIZER PRODUCTS INC. (4)
6344481 Thyromimetic antiobesity agents		6	2000
6787652 6-Azauracil derivatives as thyroid receptor ligands		8	2000
6441015 Tetrazole compounds as thyroid receptor ligands		6	2001
6664291 Malonamic acids and derivatives thereof as thyroid receptor ligands		5	2001
THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (1)
6716877 Method to treat chronic heart failure and/or elevated cholesterol levels		3	2003
APPLIED BIOSYSTEMS, LLC (1)
2004/0029,187 Systems and methods for detection of nuclear receptor function using reporter enzyme mutant complementation		2	2003
JOSLIN DIABETES CENTER, INC. (1)
6468755 Method for identifying compounds for treatment of insulin resistance		2	2000
AMERLITE DIAGNOSTICS LIMITED (1)
4426453 Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds		20	1981
AKZO N.V. (1)
5324522 Sustained release thyroactive composition		26	1992
Rega Stichting v.z.w. (1)
5663159 Prodrugs of phosphonates		98	1994
Southern Arizona Veterans Affairs Health Care System (1)
6534676 Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same		7	2001
MERCK SHARP & DOHME CORP. (1)
6680340 Anti-hypercholesterolemic drug combination		2	2003
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (1)
5571840 Method for treating central nervous system ischemia		27	1994
ALTERGON S.A. (SWISS JOINT STOCK COMPANY) (1)
2004/0219,218 Pharmaceutical formulae for thyroid hormones and procedures for obtaining them		3	2003
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (5)
6236946 Nuclear receptor ligands and ligand binding domains		5	1996
5883294 Selective thyroid hormone analogs		15	1997
6266622 Nuclear receptor ligands and ligand binding domains		4	1997
6107517 Thyroid hormone analogues and methods for their preparation		3	1999
6555582 Eye treatments using synthetic thyroid hormone compositions		5	1999
KOO, CATHERINE, DR (3)
6221911 Uses for thyroid hormone compounds or thyroid hormone-like compounds		21	1998
6380255 Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds		5	2000
2002/0123,521 Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds		4	2002
METABASIS THERAPEUTICS, INC. (2)
* 7514419 Phosphorus-containing thyromimetics		5	2005
2006/0046,980 Novel phosphorus-containing thyromimetics		10	2005
Ono Pharmaceutical Co., Ltd. (1)
* 6495533 Drugs containing phosphoric acid derivatives as the active ingredient		2	2001
BRISTOL-MYERS SQUIBB COMPANY (7)
6414002 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method		57	2001
6727271 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method		38	2002
6673815 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method		46	2002
6831102 Phenyl naphthol ligands for thyroid hormone receptor		4	2002
6747048 Pyridine-based thyroid receptor ligands		4	2003
6875782 Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method		18	2003
2005/0004,184 Thyroid receptor ligands		5	2004
NIPPON ZOKI PHARMACEUTICAL CO., LTD. (1)
5116828 Pharmaceutical composition for treatment of osteoporosis		41	1990
Warner-Lambert Company (1)
6545150 Certain benzothiazine dioxide endothelin antagonists and processes for their preparation		1	2001
Octamer, Inc. (1)
5922775 Method of treating malignant tumors with ketone thyroxine analogues having no significant hormonal activity		11	1997
Arthromics plc (1)
6414026 Compounds which interact with the thyroid hormone receptor for the treatment of fibrotic disease		10	2001
Smith Kline & French Laboratories Limited (4)
4766121 Pyridyl and pyridazinyl substituted thyronine compounds having selective thyromimetic activity		25	1986
4826876 Chemical compounds having selective thyromimetic activity		17	1987
4910305 Pyridyl and pyridazinyl substituted thyronine compounds		14	1988
5061798 Benzyl pyridyl and pyridazinyl compounds		19	1989
Bayer Aktiengesellschaft (3)
6608049 Indazoles		6	2001
6794406 Indole derivatives		4	2001
7015246 Benzofuran derivatives		2	2002
BTG INTERNATIONAL INC. (1)
5158978 Thyroid hormone treatment of acute cardiovascular compromise		34	1991
REGENERON PHARMACEUTICALS, INC. (1)
2004/0142,868 Method of treating liver steatosis in a mammal		2	2004
MERCK & CO., INC. (1)
* 5519163 Inhibitors of phosphoinositide-specific phospholipase C		4	1993
LIGAND PHARMACEUTICALS INCORPORATED (1)
6566372 Bicyclic androgen and progesterone receptor modulator compounds and methods		40	2000
KARO BIO AB (4)
5854282 3-benzoyl benzofuran derivatives as thyroid hormone antagonists		11	1997
* 6465687 Thyroid receptor ligands and method		3	2000
6492424 Glucocorticoid and thyroid hormone receptor ligands for the treatment of metabolic disorders		2	2001
6806381 Process for the preparation of aniline-derived thyroid receptor ligands		4	2002
Boehringer Mannheim GmbH (1)
4423227 Process for the preparation of reactive, couplable derivatives of the thyroid hormones		3	1981
Shionogi & Co., Ltd. (1)
2003/0153,513 Preventives or remedies for obesity or fatty liver		3	2003

* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info	(Count)	# Cites	Year
METABASIS THERAPEUTICS, INC. (1)
* 2010/0081,634 Novel Phosphorus-Containing Thyromimetics		1	2006
DOW GLOBAL TECHNOLOGIES LLC (4)
8201615 Heat storage devices		4	2009
* 8091613 Thermal energy storage materials		5	2009
* 2009/0250,189 HEAT STORAGE DEVICES		20	2009
8590598 Devices for storing and discharging heat and methods thereof		1	2012
LORD CORPORATION (2)
* 8859098 Acrylic adhesion promoters		0	2012
* 2013/0309,508 ACRYLIC ADHESION PROMOTERS		0	2012

* Cited By Examiner

Maintenance Fees

Fee	Large entity fee	small entity fee	micro entity fee	due date
7.5 Year Payment	$3600.00	$1800.00	$900.00	May 9, 2018
11.5 Year Payment	$7400.00	$3700.00	$1850.00	May 9, 2022

Fee	Large entity fee	small entity fee	micro entity fee
Surcharge - 7.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge - 11.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
November 09, 2010	US,7829552,B2   US7829552B2	GRANTED PATENT AS SECOND PUBLICATION
May 07, 2009	US,20090118236,A1   US20090118236A1	FIRST PUBLISHED PATENT APPLICATION

Full Text

US Patent No: 7829552

Phosphorus-containing thyromimetics

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