Crystals of whole antibodies and fragments thereof and methods for making and using them
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United States of America Patent
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Nov 16, 2010
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app pub date -
Dec 26, 2001
filing date -
Dec 28, 2000
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Abstract
This invention relates to crystals of whole antibodies and fragments thereof, and formulations and compositions comprising such crystals. More particularly, methods are provided for the crystallization of high concentrations of whole antibodies, and fragments thereof, in large batches, and for the preparation of stabilized whole antibody crystals for use alone, or in dry or slurry formulations or compositions. This invention also relates to methods for stabilization, storage and delivery of biologically active whole antibody crystals.
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