Antibody composition-producing cell in which enzyme expression is inhibited by RNAi

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7846725
APP PUB NO 20080261301A1
SERIAL NO

12060617

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Abstract

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The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, wherein the expression of GDP-mannose 4,6-dehydrogenase is inhibited by RNA interference.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
KYOWA HAKKO KIRIN CO., LTD.TOKYO275

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hanai, Nobuo Machida, JP 94 1645
Hosaka, Emi Machida, JP 45 1092
Kanda, Yutaka Machida, JP 78 1391
Nakamura, Kazuyasu Machida, JP 80 1425
Satoh, Mitsuo Machida, JP 51 1018
Shinkawa, Toyohide Machida, JP 35 1128
Uchida, Kazuhisa Machida, JP 46 1207
Yamane, Naoko Machida, JP 35 1051
Yamano, Kazuya Machida, JP 40 746
Yamasaki, Motoo Machida, JP 86 1380

Cited Art Landscape

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* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
BIOWA, INC. (1)
8501176 Methods of reducing eosinophil levels 3 2011
 
KYOWA HAKKO KIRIN CO., LTD. (14)
8067232 Antibody composition-producing cell with inactivated A-1,6-fusocyltransferase 0 2008
* 2008/0227,196 Antibody Composition-Producing Cell 4 2008
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8895266 Antibody composition-producing cell 1 2012
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ASTRAZENECA AB (3)
9441037 Methods for reducing exacerbation rates of asthma using benralizumab 0 2014
9441046 Methods for increasing forced expiratory volume in asthmatics using benralizumab 0 2014
9441047 Methods for improving asthma symptoms using benralizumab 0 2014
* Cited By Examiner

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