US Patent No: 7,853,329

Number of patents in Portfolio can not be more than 2000

Monitoring efficacy of neural modulation therapy

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Abstract

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A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
CYBERONICS, INC.HOUSTON, TX217

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DiLorenzo, Daniel John Seattle, US 36 3469

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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6,760,626 Apparatus and method for treatment of neurological and neuropsychiatric disorders using programmerless implantable pulse generator system 223 2001
6,879,859 External pulse generator for adjunct (add-on) treatment of obesity, eating disorders, neurological, neuropsychiatric, and urological disorders 167 2002
2005/0143,787 Method and system for providing electrical pulses for neuromodulation of vagus nerve(s), using rechargeable implanted pulse generator 237 2005
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (2)
4,955,380 Flexible measurement probes 66 1988
7,212,851 Microstructured arrays for cortex interaction and related methods of manufacture and use 58 2002
 
NEUROPACE, INC. (29)
6,061,593 EEG d-c voltage shift as a means for detecting the onset of a neurological event 278 1998
5,938,689 Electrode configuration for a brain neuropacemaker 160 1998
6,006,124 Means and method for the placement of brain electrodes 239 1998
6,161,045 Method for determining stimulation parameters for the treatment of epileptic seizures 185 1999
6,230,049 Integrated system for EEG monitoring and electrical stimulation with a multiplicity of electrodes 190 1999
6,128,538 Means and method for the treatment of neurological disorders 300 1999
6,134,474 Responsive implantable system for the treatment of neurological disorders 341 2000
6,473,639 Neurological event detection procedure using processed display channel based algorithms and devices incorporating these procedures 302 2000
6,466,822 Multimodal neurostimulator and process of using it 280 2000
6,427,086 Means and method for the intracranial placement of a neurostimulator 258 2000
6,353,754 System for the creation of patient specific templates for epileptiform activity detection 172 2000
6,354,299 Implantable device for patient communication 219 2000
6,360,122 Data recording methods for an implantable device 275 2000
6,591,138 Low frequency neurostimulator for the treatment of neurological disorders 192 2000
7,089,059 Predicting susceptibility to neurological dysfunction based on measured neural electrophysiology 181 2000
6,529,774 Extradural leads, neurostimulator assemblies, and processes of using them for somatosensory and brain stimulation 212 2000
6,591,137 Implantable neuromuscular stimulator for the treatment of gastrointestinal disorders 233 2000
6,597,954 System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes 313 2000
6,618,623 Ferrule for cranial implant 109 2000
6,480,743 System and method for adaptive brain stimulation 415 2001
2003/0144,711 Systems and methods for interacting with an implantable medical device 153 2002
2002/0099,412 Methods for using an implantable device for patient communication 203 2002
2002/0169,485 Differential neurostimulation therapy driven by physiological context 283 2002
2003/0195,588 External ear canal interface for the treatment of neurological disorders 178 2002
2003/0028,072 Low frequency magnetic neurostimulator for the treatment of neurological disorders 115 2002
2004/0153,129 System and method for controlling neurological disorders with spatially separated detection and therapy locations 134 2003
2005/0222,641 Neurostimulator involving stimulation strategies and process for using it 48 2005
* 2006/0212,092 Systems and methods for interacting with an implantable medical device 41 2006
2006/0212,093 Differential neurostimulation therapy driven by physiological therapy 43 2006
 
Flint Hills Scientific, LLC (4)
6,341,236 Vagal nerve stimulation techniques for treatment of epileptic seizures 546 1999
6,560,486 Bi-directional cerebral interface system 151 1999
6,768,969 Method, computer program, and system for automated real-time signal analysis for detection, quantification, and prediction of signal changes 119 2001
6,934,580 Stimulation methodologies and apparatus for control of brain states 177 2003
 
JPMORGAN CHASE BANK, N.A. (1)
2002/0062,071 Manual and automatic probe calibration 18 2001
 
NEW YORK UNIVERSITY (3)
4,279,258 Rapid automatic electroencephalographic evaluation 119 1980
4,545,388 Self-normed brain state monitoring 48 1983
6,052,619 Brain function scan system 145 1997
 
ADVANCED BIONICS, LLC (1)
6,411,854 Implanted ceramic case with enhanced ceramic case strength 38 1999
 
Bionova Technologies Inc. (1)
7,373,198 Method and apparatus for the estimation of anesthetic depth using wavelet analysis of the electroencephalogram 36 2003
 
Mayo Foundation for Medical Education and Research Image -Guided Neurologics, Inc. (1)
2007/0250,077 DEVICE FOR IMMOBILIZING A PRIMARY INSTRUMENT AND METHOD THEREFOR 39 2007
 
GEORGE MASON UNIVERSITY (1)
6,665,562 Adaptive electric field modulation of neural systems 119 2000
 
The McLean Hospital Corporation (1)
6,572,528 Magnetic field stimulation techniques 80 2001
 
CHILDREN'S MEDICAL CENTER CORPORATION (4)
4,407,299 Brain electrical activity mapping 66 1981
4,408,616 Brain electricaL activity mapping 62 1981
4,421,122 Brain electrical activity mapping 76 1981
RE34015 Brain electrical activity mapping 108 1987
 
ZIMMER BIOMET CMF AND THORACIC, LLC (1)
5,578,036 Method and apparatus for fixation of bone during surgical procedures 105 1993
 
LIFEWATCH TECHNOLOGIES, INC. (1)
5,931,791 Medical patient vital signs-monitoring apparatus 328 1997
 
CVRX, INC. (1)
2005/0096,710 Baroreceptor activation for epilepsy control 137 2004
 
APREX CORPORATION (1)
5,917,429 Contactless communication system 87 1996
 
EnteroMedics Inc. (1)
2005/0070,970 Movement disorder stimulation with neural block 88 2004
 
RDM Consultants Ltd. (1)
5,816,247 Monitoring an EEG 58 1996
 
ADVANCED BRAIN MONITORING, INC. (1)
6,496,724 Method for the quantification of human alertness 66 1999
 
CASE WESTERN RESERVE UNIVERSITY (1)
5,167,229 Functional neuromuscular stimulation system 164 1986
 
BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (1)
6,339,725 Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation 203 2000
 
JORDAN NEUROSCIENCE, INC. (1)
6,510,340 Method and apparatus for electroencephalography 79 2001
 
MEDSERV GROUP, INC. (1)
5,549,656 Combination neuromuscular stimulator and electromyograph system 196 1995
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
CYBERONICS, INC. (6)
8,849,390 Processing for multi-channel signals 0 2009
8,588,933 Medical lead termination sleeve for implantable medical devices 1 2010
8,786,624 Processing for multi-channel signals 0 2010
8,543,199 Implantable systems and methods for identifying a contra-ictal condition in a subject 1 2011
9,445,730 Implantable systems and methods for identifying a contra-ictal condition in a subject 0 2013
9,289,595 Medical lead termination sleeve for implantable medical devices 0 2013
 
Flint Hills Scientific, LLC (2)
* 8,560,073 System and apparatus for automated quantitative assessment, optimization and logging of the effects of a therapy 1 2010
* 2011/0160,795 SYSTEM AND APPARATUS FOR AUTOMATED QUANTITATIVE ASSESSMENT, OPTIMIZATION AND LOGGING OF THE EFFECTS OF A THERAPY 3 2010
 
NEUROPACE, INC. (8)
8,073,544 Neurostimulator involving stimulation strategies and process for using it 4 2005
8,412,333 Neurostimulator involving stimulation strategies and process for using it 0 2011
8,326,417 Neurostimulator involving stimulation strategies and process for using it 0 2011
8,224,452 Differential neurostimulation therapy driven by physiological therapy 1 2011
8,423,145 Differential neurostimulation therapy driven by physiological therapy 2 2012
8,694,106 Neurostimulator involving stimulation strategies and process for using it 0 2013
8,934,980 Differential neurostimulation therapy driven by physiological therapy 0 2013
9,451,891 Differential neurostimulation therapy driven by physiological therapy 0 2014
 
BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (5)
* 8,155,750 System and method for avoiding, reversing, and managing neurological accommodation to electrical stimulation 10 2009
* 2010/0023,090 SYSTEM AND METHOD FOR AVOIDING, REVERSING, AND MANAGING NEUROLOGICAL ACCOMODATION TO ELETRICAL STIMULATION 9 2009
* 8,315,707 System and method for avoiding, reversing, and managing neurological accommodation to electrical stimulation 0 2012
* 2012/0179,222 SYSTEM AND METHOD FOR AVOIDING, REVERSING, AND MANAGING NEUROLOGICAL ACCOMMODATION TO ELECTRICAL STIMULATION 5 2012
8,660,644 System and method for avoiding, reversing, and managing neurological accommodation to electrical stimulation 0 2012
 
DIGNITY HEALTH (3)
9,289,599 Vagus nerve stimulation method 0 2012
9,108,041 Microburst electrical stimulation of cranial nerves for the treatment of medical conditions 0 2013
9,533,151 Microburst electrical stimulation of cranial nerves for the treatment of medical conditions 0 2014
 
Catholic Healthcare West (1)
8,738,126 Synchronization of vagus nerve stimulation with the cardiac cycle of a patient 2 2009
* Cited By Examiner

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