Extended release composition containing Tramadol
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United States of America Patent
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Dec 28, 2010
Grant Date -
Jul 31, 2003
app pub date -
Apr 11, 2002
filing date -
Apr 11, 2001
priority date (Note) -
In Force
status (Latency Note)
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Abstract
An oral Tramadol-containing pharmaceutical composition suitable for once daily administration, which contains an amount of Tramadol or a pharmaceutically acceptable salt thereof, providing in vivo, a time of Tramadol peak plasma concentration (T.sub.max) of greater than 10 hours, and peak Tramadol plasma concentration (C.sub.max) which are less than three times the plasma concentration obtained 24 hours after administration (C.sub.24h) of a single dose of the composition.
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