Importance

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Abstract

each independently represents the same or a different naturally occurring amino acid residue other than cysteine, “a” represents an integer between 2 and 6, “b” represents an integer between 3 and 7, “c” represents an integer between 7 and 11, “d” represents an integer between 0 and 4, “e” represents an integer between 1 and 6, “f” and “g” represent integers between 8 and 12, “h” represents an integer between 4 and 8, and “i” represents an integer between 11 and 15) and has 50% or more homology with the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 29; and (c) selectively inhibits GDF-8 activity as compared with its inhibition of activin activity.

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First Claim