Biointerface membranes incorporating bioactive agents
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United States of America Patent
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Jan 25, 2011
Grant Date -
Feb 10, 2005
app pub date -
May 10, 2004
filing date -
May 21, 2003
priority date (Note) -
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Abstract
A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.
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