Hedgehog antibodies
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United States of America Patent
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Mar 8, 2011
Grant Date -
Dec 22, 2005
app pub date -
Aug 3, 2005
filing date -
Dec 30, 1993
priority date (Note) -
Expired
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Abstract
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.
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